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These host pathways include various metabolic pathways such as glycolysis, pentose phosphate pathway, glutamine metabolism, fatty acid oxidation, Kreb cycle, and oxidative phosphorylation ( Glutamine is the most abundant amino acid in the human body Glutamine is the most abundant amino acid of all 20 amino acids in the human body

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doi: 10.1007/s40263-022-00907-3

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With respect to cell-mediated immunity, retinol is important in the activation of T cells (73), and vitamin A deficiency may affect cell-mediated immunity by decreasing the number or distribution of T cells, altering cytokine production, or by decreasing the expression of cell-surface receptors that mediate T-cell signaling (56)