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Implications for Health and Lifespan Improving healthspan is directly associated with a decrease in cellular senescence, which presents the prospect of increasing life expectancy rather than merely life expectancy

The reduction in red blood cell production is why patients with B12 deficiency report feeling so extremely fatigued (even under the slightest of efforts), sort of like the fatigue you get from altitude sickness

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MTHFR deficiencies lead to a shortage of the active form of folate within the body and negatively impacts the conversion of homocysteine to methionine

Allow 2-4 weeks to assess tolerance before increasing