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Therapeutic regimens tailored to each patients genetic background, immune status, and gut microbial signature are expected to enhance efficacy while minimizing adverse effects and treatment burden

27% of patients had well-differentiated tumor, while 63% and 9% had moderate and poor/undifferentiated tumor, respectively

who were not taking medications that affect muscle mass or liver function, did not have severe disease or physical condition that could interfere the intervention

There is evidence that in ovarian cancer, the enzyme indoleamine 2,3-dioxygenase (IDO) catalyzes the breakdown of tryptophan through the kynurenine pathway, resulting in immunosuppressive compounds that accelerate the growth of tumor cells and reduce antitumor immunity (109, 110)

SparksJABarbhaiyaMTedeschiSKLeatherwoodCLTabungFKSpeyerCBet al

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