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Cell Mol Gastroenterol Hepatol 12(1):229250 Kim KC, McCracken K, Lee BC et al (1997) Airway goblet cell mucin: its structure and regulation of secretion

Patients presenting after two weeks may still benefit if disease progression is active or severe

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However, it is important not to overlook the fact that cancer is a vast group of diseases that may vary substantially among them

GSH depletion influences the capacity of cells to scavenge free radicals, a fact that makes cells vulnerable to secondary events such as accumulation of ROS and alteration in Ca 2+ homeostatic mechanisms resulting in cell death (Fukui et al., 2009)