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Agents that cause depletion of catecholamines from the sympathetic nerve terminals (e.g., reserpine) can also antagonize indirectly acting agents (such as tyramine) because there is a lack of catecholamines to be released

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Rapamycin-induced autophagy ameliorates GSH depletion-induced premature cell senescence It was shown that autophagy activation especially in the presence of an increasing autophagic flux inhibits the senescence of RPE cells 35,36,37,38,39

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doi: 10.1016/0165-1161(75)90046-1 210 ColmanNHerbertVGardnerAGelerntM

Molecular characterization, regulation, heterologous expression, and enzyme properties