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Bmj 384, e077169

Peer review Peer review information Nature Reviews Nephrology thanks B

In personal communication with the authors, they state the relief of symptoms is due to lowering of pressure on the venous system suggesting that venous disease is important in the diagnosis of lipohypertrophy

CoA is also needed for FA mitochondrial intake through CPT and for KB synthesis in the liver as well as for FA synthesis in the cytoplasm

Fatty strips formation For a clear understanding of how ox-LDL leads to atherosclerosis, there is a need to explain the whole mechanism of atherosclerosis (48)