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At the early stages of RD, retinal gene therapy appears to be one of the most important strategies before the complete loss of photoreceptors

Murtola TJ, Tammela TL, Maattanen L, Huhtala H, Platz EA, Ala-Opas M et al

Apoptosis-associated GSH efflux A pronounced intracellular GSH efflux is a functionally required event during apoptosis, preceding ROS generation 41

It achieves this by covalently binding to and inhibiting Dicer, a critical RNase responsible for cleaving and loading precursor miRNAs into mature miRNAs

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J Trace Elements Med Biol 37:824 Khosravi-Darani K, Rehman Y, Katsoyiannis IA, Kokkinos E, Zouboulis AI (2022) Arsenic exposure via contaminated water and food sources