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Mutations in DDHD2, encoding an intracellular phospholipase A1, cause a recessive form of complex hereditary spastic paraplegia

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These smart agents minimize off-target toxicity while maximizing reactive oxygen species production at disease sites, thereby enhancing therapeutic efficacy and safety [74]

This approach significantly improved angiogenesis and accelerated wound repair in diabetic models, underscoring the role of mitochondrial dysfunction in NET-mediated pathology

Once the injection is complete, the patient should apply pressure to the injection site for a few minutes to minimize bruising and discard the used syringe in the sharps container

This generally means that excess amounts are excreted in the urine, rather than being stored in the body, per NCI Dictionary of Cancer Terms