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These results may provide new ways for designing novel antifibrotic therapies for CsA-induced gingival growth by targeting Snail [35]

Loren Pickart, the researcher responsible for its original isolation, has stated that in his numerous studies on GHK, no issues have ever arisen during its use as a skin cosmetic or in human wound healing studies [13]. But that is not to say that GHK-Cu is completely without side effects

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Note that reconstituted injectable GHK-Cu can be used topically, but topical copper peptide products formulated for skin application may include additional ingredients optimizing penetration and stability that simple water reconstitution doesn't provide

Both estrogen receptor and stimulate pituitary GH gene expression