glutathione glutathione peroxidase Reaction mechanism of (GPX) Glutathione peroxidase 1 - Wikipedia

As the core antagonist of lipid peroxidation, GPX4 converts toxic lipid hydroperoxides (L-OOH) into inert lipid alcohols (L-OH) by consuming the reducing power provided by GSH, effectively blocking the propagation of radical chain reactions ( - ) ( - ( 2.4 The critical role of mitochondria in ferroptosis As a core regulatory hub of ferroptosis, mitochondrial dynamic structural and functional disorders run through the entire process of ferroptosis ( 2.5 The dynamic regulatory network of ferroptosis signaling pathways 2.5.1 Oxidative stress response pathway Nrf2, as the central hub of antioxidant defense, binds to Keap1 and is continuously degraded in a resting state ( - , leading to the interruption of GSH synthesis and the inactivation of GPX4 ( 2.5.2 Energy metabolism pathway In the metabolic regulatory network of ferroptosis, the dynamic balance of the energy metabolism pathway profoundly affects the process of lipid peroxidation

The SPSS statistical program was adopted, with a significance level of 5%

Some other small molecule compounds (Table 2) such as alloimperatorin (Zhang J

The MIC injection is a non-prescription nutrient blend offering supportive nutrients only

AITC increases the amount of LC3-II protein in RV1 and PC3 cells over time, promoting autophagy

AI algorithms analyzed the collected data to identify key factors affecting quality of life and generate recommendations for rehabilitation