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Their further study showed that the presence of a cysteine/cystine shuttle between neighboring cells is the mechanism that provides redox and nutrient balance, and thus ferroptotic resistance in SLC7A11 knock out PDAC cells (Meira et al., 2021)

Life 2019, 9, 59

Liu, K, Titt, U, Esplen, NM, Connell, L, Konradsson, E, Yang, M, Wang, X, Takaoka, T, Li, Z, Koong, A, Mitra, D, Mohan, R , Loo, BW, Lin, SH, Schueler, E

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Such studies would also provide more information on its long-term safety and efficacy