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D.BassettP.AbbaraA.et al (2023a)

doi:10.1186/s12906-022-03729-4 198

Shock (2011) 36(1):978

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Additionally, metabolic interventions such as caloric restriction mimetics (e.g., spermidine, -ketoglutarate, ergothioneine) enhance mitochondrial function, activate autophagy, and reprogram energy metabolism, demonstrating lifespan extension and healthspan improvement in preclinical models