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Human cohort studies are relatively small

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Figure 3 Throughout our in vitro experiments, we exposed activated ILC2s to a pharmacological concentration (250M) of melatonin as has been shown previously to be maximally effective in driving phenotypic changes in T-cells without causing toxicity ( Figures 3F, G ), and was additionally required to produce maximal suppression of ILC2 activity ( Figures 3H, I )

Fur from the animal may impede the measurement

10.1016/j.celrep.2017.12.077 95 TeufelD

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