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Ohbu M, Kobayashi N, Okayasu I

Furthermore, kidneys from PKD1-knockout mice exhibit prominent features of ferroptosis, including the downregulation of SLC3A2, SLC7A11, and GPX4 and the upregulation of TFR1, divalent metal transporter 1, and HO-1, as well as mitochondrial abnormalities such as reduced mitochondrial cristae and ruptured mitochondrial outer membranes

doi: 10.1105/tpc.113.120642

CoA engages in numerous metabolic processes in the body

GCN2 protein kinase is required to activate amino acid deprivation responses in mice treated with the anti-cancer agent L-asparaginase

doi: 10.1016/j.annemergmed.2008.03.016