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Neutropenia associated with iron chelation therapy and potential hepatic/renal toxicity underscore the importance of continuous monitoring of organ function during clinical application

In 2009, we proposed the trypanocidal mechanism of action of naphthofuranquinones

doi: 10.1111/j.1346-8138.1991.tb03079.x

As expected, the fumarate concentration was 1.62.0-times higher in the tumour compared to the normal kidney (normal kidney: 5.9 10 4 a.u

These mechanisms work together to inhibit mTORC1-mediated fat and protein synthesis, and this inhibition synergizes with AMPK-driven catabolism to maintain dynamic energy metabolism balance and improve MAFLD

The results show that both the unencapsulated APIs and EV-QuerCar exhibit uniform permeation rates from 0 to 8 h