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Mutat Res Fund Mol Mech Mutagen

Collectively, these findings underscore the regulatory role of PSPH, facilitating the increased expression of galectin-1, offering therapeutic opportunities to overcome phenotypically immunosuppressive GBMs, and augment the efficacy of immunotherapies

269 High-mobility group box protein 1 (HMGB1)/Toll-like receptor (TLR) and NF-B signaling pathways in neuroinflammation Various immune cells, as well as the corresponding cellular products, are associated with oxidative stress and necrosis activate the innate immune system, probably via the TLR signaling pathway

doi: 10.1161/CIRCULATIONAHA.113.003058 289 GuoYZhangXHuangWMiaoX

It is also an essential co-factor in the liver for detoxing

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