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The cell membranes were isolated by ultracentrifugation at 100,000 g for 30 min at 4 C

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26 These reductive reactions generate the oxidized form of GSH, GSH disulfide (GSSG)

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Although several positive outcomes were observed during the trials, indicating at least some progress toward a better understanding of the disease and a treatment for patients, discrepancies between the data obtained in men and mice were common: benefits experienced by patients were often very subtle, limited to subgroups, outside the outcome measures or simply absent

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4and 5) similarly to the uptake of 3-PLG-A-GSH without cargo in our previous paper [24]

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