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Potential for Combining Antioxidants with Emerging Therapies : Antioxidants may enhance the efficacy of several treatment modalities, including immunotherapy, photodynamic therapy, gene therapy, and synergistic combinations

Underscoring the significance of this GAPDH/Siah cell death cascade is the demonstration that the anti-Parkinsons disease drug deprenyl, which reduces neuronal cell death in both in vitro and in vivo models, prevents S-nitrosylation of GAPDH, blocks the GAPDHSiah interaction, and inhibits GAPDH nuclear translocation (90)

Effect of catalpol on oxidative stress response in the liver of mice with hyperthyroidism

Administration of oleuropein augmented the levels of GSH and CAT while diminution of NO and secretion of tumor necrotic factor-alpha and vascular endothelial growth factor expression

Rahman MB, Hussain M, Kabiraz MP, Nordin N, Siddiqui SA, Bhowmik S, et al