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For example, activated IRE1 and recruited TRAF2 activate JNK, inducing the production of IL-6 and TNF- by phosphorylation of AP-1 and consequent NF-B activation

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SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan

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Ectopic lipid deposition in liver, skeletal muscle, and pancreatic tissue progressively impairs systemic glucose regulation and insulin sensitivity (368)

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ZhangFTangBZhangZXuDMaG.DUSP6 Inhibitor (E/Z)-BCI hydrochloride attenuates lipopolysaccharide-induced inflammatory responses in murine macrophage cells via activating the Nrf2 signaling axis and inhibiting the NF-B pathway

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