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Despite that the exact pathophysiology of ATL is still unclear, it is hypothesized that the effect of the toxic agent in ATL may lead to a damage in the white matter either by direct injury of the myelin sheath and/or indirect injury on the capillary endothelium [17]

Erythrocyte phenylalanine concentrations showed similar changes (Stegink et al., 1981a)

254 In another study, metformin was able to attenuate hyperhomocysteinemia-induced cardiac hypertrophy by decreasing myocardial fibrosis

Because there is not enough high-quality human evidence to support routine clinical use and they are not currently approved for use in Humans by Health Canada or the FDA

doi: 10.3389/fnins.2025.1514253 Received 20 October 2024 Accepted 27 January 2025 Published 05 March 2025 Volume 19 - 2025 Edited by David Mokler, University of New England, United States Reviewed by Yuanbo Pan, Zhejiang University, China Tang Tao, Sun Yat-sen University Cancer Center (SYSUCC), China Updates Copyright 2025 Chang, Liu, Xiao, Tan, Deng, Mei and Liao

Therefore, FSP1 has a good application prospect in the ferroptosis of lung cancer