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Table 2 shows patients' main baseline characteristics and outcome measures

8.2.2 Dysregulated calcium homeostasis As calcium (Ca 2+ ) is a ubiquitous signaling molecule and particularly important for function of sensory neurons, it is perhaps not surprising that evidence of dysregulated Ca 2+ homeostasis has been reported for several chemotherapeutics, including oxaliplatin, cisplatin, paclitaxel, bortezomib and vincristine (Tomaszewski and Busselberg, 2007

Chemotherapy-induced mucosal injury is also influenced by pro-inflammatory cytokines such as TNF, interferon- (IFN ), interleukin 1 (IL-1), and IL-6 [76, 77]