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To date, there are 8 clinical trials of varying design and size (Table 2) focused mainly on patients with advancing COVID-19 that does not require mechanical ventilation

Consistently, microarray analysis revealed that PYC altered the expression of several apoptosis- and adhesin-related genes, including Janus kinase 1, dual specificity phosphatase 1, ras homolog family member A, laminin 1, fibronectin 1, catenin alpha 1, and integrin subunit beta 1

doi: 10.1016/S0140-6736(23)01053-X

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Under GSH-depleted conditions, GSH-conjugation was two- and three-fold higher in GSTP1 -transfected cells compared to mock-transfected cells, for AQ-QI and DEAQ-QI respectively