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Transneuronal propagation of pathologic -Synuclein from the gut to the brain models Parkinsons disease

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AOCDs are frequently associated with the same genes that determine PFIC, but while in PFIC these genes behave as recessive, in adult cholestasis, they can behave as autosomal dominant, being often in the heterozygous state [22]

Overall, these pilot study findings indicate the potential therapeutic liver metabolism and function benefits associated with oral administration of glutathione in individuals with early NAFLD without decompensated cirrhosis