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doi: 10.1016/j.molcel.2017.05.030 106 ZhangYSwandaRVNieLLiuXWangCLeeHet al

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Cp nc, cp m, cng trn mng nc

Human GSTs are classified into two distinct categories: Soluble or cytosolic and membrane-bound microsomal

Importantly, response seems more closely tied to biology (inflammation, obesity) than to the MTHFR genotype alone

Mutations of somatic mtDNA control region (CR) increase with age in postmitotic tissues including the brain, and the level of mtDNA mutations is significantly elevated in the brains of AD patients