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Authors' contributions The authors' responsibilities were as follows--QG and JLF conceived and researched the review

Theres no research showing that someone with one copy of an ACADVL mutation should limit long-chain fats

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However, some modalities appear to show potential, with ESWT and traction therapies demonstrating some improvements in improving pain and curvature respectively

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Conclusion L-carnitine + synbiotic co-supplementation was more beneficial in ameliorating anthropometric indices as well as some cardiometabolic parameters compared with L-carnitine single therapy, suggesting that it is a promising adjuvant approach to ameliorate obesity or associated metabolic complications through potential synergistic or complementary mechanisms