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PFR demonstrated the most pronounced reduction in ROS levels, particularly in cells subjected to ethanol and nicotine exposure, highlighting potent AOx capacity [81]

Likewise, caffeic acid itself directly inhibited ERK1/2 (MAPK) activity in melanoma and epidermoid carcinoma cells, disrupting a key pathway that promotes tumor growth and migration (150)

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Yurgelun MB, Chittenden AB, Morales-Oyarvide V, Rubinson DA, Dunne RF, Kozak MM, Qian ZR, Welch MW, Brais LK, Da Silva A, Bui JL, Yuan C, Li T, Li W, Masuda A, Gu M, Bullock AJ, Chang DT, Clancy TE, Linehan DC, Findeis-Hosey JJ, Doyle LA, Thorner AR, Ducar MD, Wollison BM, Khalaf N, Perez K, Syngal S, Aguirre AJ, Hahn WC, Meyerson ML, Fuchs CS, Ogino S, Hornick JL, Hezel AF, Koong AC , Nowak JA, Wolpin BM

[PubMed] [Google Scholar] 52.Cuypers MD, Grooters AM, Williams J, Partington BP

This vitamin is essential for boosting HDL cholesterol, which also lowers the amount of bad cholesterol in the body