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NNMT methylates nicotinamide (a form of vitamin B3) using S-adenosylmethionine (SAM) as the methyl donor

Choline is an essential amino acid that helps move fat and bile from the liver

Once NAM undergoes methylation by NNMT, it becomes unavailable for NAD + generation via the salvage pathway

Patients with Normal Intestinal Absorption: Where the oral route is not deemed adequate, initial treatment similar to that for patients with pernicious anemia may be indicated depending on the severity of the deficiency

This depends on how severe the deficiency is and how well the patient responds to treatment

Inositol: Another crucial ingredient that assists in turning food into energy