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The main ongoing studies: REDEFINE 1 , Phase 3 obesity without T2D (results 20242025, preliminarily 25.3 %) REDEFINE 2 , Phase 3 obesity + T2D REDEFINE 3 , Phase 3 cardiovascular outcome trial (n~7000) Stand-alone clinical development of Cagrilintide is limited , Novo Nordisk is primarily investing in the CagriSema combination

Week-by-week Retatrutide timeline showing when results start, peak side effects (weeks 6-8), and final outcomes

doi:10.1093/jn/137.1.25 [82] Chan WY, Rennert OM

[DOI] [PubMed] [Google Scholar] 82.Ebesunun M.O., Obajobi E.O

Rare adverse events that might emerge in large systematic studies could remain invisible in informal self-experimentation

No laterality