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Previously, we observed a correlation between nuclear FOXO3 and high caspase-8 expression, which induces cellular apoptosis in response to harmful external stimuli

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To elucidate whether EULE-mediated lifespan extension operates via MAPK pathway activation, RT-qPCR analysis was conducted to quantify the transcript levels of pivotal MAPK components in wild-type N2 C

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*Correspondence: Lidan Hu, [email protected] This article was submitted to Nanobiotechnology, a section of the journal Frontiers in Bioengineering and Biotechnology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers