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Effect of NNMT Inhibitor on Adipocyte Differentiation Quantitated with Oil Red O Staining

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Semaglutide tends to produce weight loss measurable in weeks to months with a distinct path to significant outcomes, while AOD-9604 can exhibit slower and more modest fat-specific impacts over an extended period

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In vitro experiments demonstrated that NNMT overexpression significantly increased Sirt1 protein expression in primary hepatocytes, while NNMT knockdown led to a notable decrease in Sirt1 protein expression