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Intracellular Mechanisms of HC Loss Free Radical Accumulation and Calcium Homeostasis Generation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) in the cochlea are triggered by exposure of loud sound and ototoxic drugs often followed by caspase-mediated cell death by apoptosis (Shi and Nuttall, 2003

Patients who received medium and high doses of these cells showed significant improvement in motor function without serious complications

Lymph Node Ratio is Associated with Time to Pulmonary Metastasis in Patients with Resected Colorectal Cancer, 2022

The acid-responsive iron-based nanocomposite UPM (USPBNPs@MCSNs) exhibits dual enzymatic activity in weakly acidic environments, generating toxic OH to kill tumor cells, while releasing O 2 in neutral environments to alleviate hypoxia

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This study presents a novel DEC that concurrently targets oxidative stress (via ergothioneine and tocopheryl glucoside) and glycation (via decarboxy carnosine and naringin), demonstrating its efficacy in suppressing melanogenesis across clinical, cellular, and 3D skin models