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113 Central Nervous System Drug Administration and the Blood-Brain Barrier Some speculate that strong selective pressure must have existed to allow such a complex structure as the BBB to evolve

There were multiple studies that lacked a control group (important in understanding whether a drug actually worked or if it was a placebo effect) and sample sizes of less than 20 people (running the risk that this might be a chance finding that wouldnt apply to the general population)

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These experiments suggest that Epithalon may be useful in exploring mechanisms of photoreceptor preservation, retinal signaling, and neuroprotective strategies in the eye

Once the therapeutic effect begun, the therapeutic effect is continuous, and neither of the continuous ligation-induced disturbances reappeared (Vukojevic et al., 2018