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Beyond repurposing existing drugs, Nrf2 activators (e.g., Dimethyl Fumarate) are particularly promising as they upstreamly regulate a network of antioxidant genes, including SLC7A11, GPX4, HO-1, and FTH1, thus simultaneously bolstering defenses against multiple drivers of ferroptosis ( Table 2 ) (176)

Philip AT, Gerson B

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Haugland RP (2005) The handbook: a guide to fluorescent probes and labeling technologies, Doctoral dissertation, Univerza v Ljubljani, Fakulteta za farmacijo Hoque TS, Hossain MA, Mostofa MG, Burritt DJ, Fujita M, Tran LSP (2016) Methylglyoxal: an emerging signaling molecule in plant abiotic stress responses and tolerance

Xu W, Wang F, Yu Z, Xin F, Epigenetics, Metabolism C

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