buthionine sulfoximine and glutathione depletion by BSO induces fat remodelling in mice. (A) GSH Development of a mouse model

Development of a mouse model expressing a bifunctional glutathione synthesizing enzyme to study glutathione limitation in vivo Journal of Biological Chemistry Methionine and Buthionine Sulfoximines: Syntheses under Mild and Safe Imidation Oxidation Conditions Buglioni 2014 Advanced Synthesis & Catalysis Wiley Online Library Hypertoxic self assembled peptide with dual functions of glutathione depletion and biosynthesis inhibition for selective tumor ferroptosis and pyroptosis Journal of Nanobiotechnology Springer Nature Link Iron based metal organic framework co loaded with buthionine sulfoximine and oxaliplatin for enhanced cancer chemo ferrotherapy via sustainable glutathione elimination Journal of Nanobiotechnology Springer Nature Link Markedly Decreased Expression of Glutathione S Transferase Gene in Human Cancer Cell Lines Resistant to Buthionine Sulfoximine, an Inhibitor of Cellular Glutathione Synthesis () Journal of Biological Chemistry Glutathione depletion induces oxidative injury and apoptosis via TRPM2 channel activation in renal collecting duct cells ScienceDirect

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