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DMF diminishes ferroptosis stress in SCD mice Previously, we showed that DMF decreases the expression of plasma proinflammatory factors such as Il1a and Tnf in SCD mice 25 (Supplementary Fig

A recent study on humans and mice demonstrated that disrupted GH signaling was associated with elevated p53 levels in colon tissue, suggesting GH may act as a tumor promoter by suppressing gene transcription of p53, PTEN, and APC levels (Friend, 2001

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Antioxidant therapy Recent human studies exploring the efficiency of antioxidants in prevention and treatment of various diseases are reviewed (Table 4)