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Both compounds target critical pathways involved in retinal disease progression, including oxidative stress, mitochondrial dysfunction, and inflammation, offering complementary therapeutic benefits

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Biomolecules 11, 1479 (2022), Abstract Asiatic acid from Cyclocarya paliurus regulates the autophagy-lysosome system via directly inhibiting TGF- type I receptor and ameliorates diabetic nephropathy fibrosis: X.X

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This is why most published dihexa research uses 7- or 14-day protocols rather than chronic administration

Lastly, trimetazidine can alleviate oxidative stress following lifestyle-related injuries