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doi: 10.1021/jp105037w

10.1056/NEJM196704272761707 100 EberhardsonM.PattersonS.GrapengiesserE

They are polarized tissues due to the differential expression of ion channels, pumps and transporters in the apical and the basolateral sides: (a) epithelial sodium channels (ENaC), Ca 2+ activated chloride channels and the cystic fibrosis transmembrane conductance regulator (CFTR) are present in the apical plasma membrane and (b) the Na + -K + -ATPase ion pump and the Na + -K + -2Cl cotransporter in the basolateral side

Van de Velde et al, 2017

Engineered bacterial membrane vesicles are promising carriers for vaccine design and tumor immunotherapy