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Sulforaphane was the first identified and most potent naturally occurring NRF2 activator found in cruciferous vegetables such as broccoli, cauliflower, and Brussel sprouts (Zhang et al., 1992

In db/db mice, dapagliflozin reshapes the gut microbiota and redirects tryptophan metabolism toward increased L-tryptophanderived metabolites, leading to augmented GLP-1 production, higher circulating GLP-1 and C-peptide levels, and expansion of -cell mass via enhanced proliferation

the study design was a standard, three-period, randomized, single-dose crossover study

Subsequently, the AREDS 2 study replaced beta carotene of the AREDS formula with 10 mg of lutein and 2 mg of zeaxanthin

(iv) Aged/non-dual eligible Medicare and Medicaid beneficiaries