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For this reason, the EO has been the target of intense research in recent years, mainly in the implications on how mitochondria produce ROS, since they are of vital importance to understand their relationship with the pathogenesis of several chronic diseases such as cancer, osteoporosis, Alzheimers, type 2 diabetes, neurodegenerative diseases, and cardiovascular diseases such as heart failure [7]

Sikiric et al., 2010

New York, NY: United Nations (1986)

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Notably, KU-57788-treated cells remained adherent, adopted a more spindle-shaped and elongated morphology, and exhibited an increase in cell size with prolonged treatment (Fig