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Beyond IVIG: A Comprehensive Approach to SFN While IVIG can be transformative for many patients, I always emphasize that it works best as part of a comprehensive treatment approach

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There are also topical, inhalant, and intravenous preparations

Thiamine also appears to have direct anti-inflammatory effects in the gut of ruminant animals, showing a reduction in intestinal permeability through enhanced production of barrier proteins, protection against bacterial lipopolysaccharide-induced inflammation, and improved barrier function