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However, total amino acid intake must be modified to a much greater extent to elicit a robust physiologic effect than we used in our mouse study with a standard control diet and the 3 Gly: 1 Pro: 1 Hyp formulation at modest doses, modifying overall protein intake by approximately 5%

doi: 10.1182/blood-2004-02-0446 113 SimardJCSimonMMTessierPAGirardD