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Neuroactive peptides work through mechanisms such as brain-derived neurotrophic factor (BDNF) upregulation, HGF/c-Met signaling, and modulation of monoamine neurotransmitters (Table 4)

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When we evaluated the degree of suicide risk, we found that serum GSH levels were significantly lower for moderate to high suicide risk than for women without suicide risk, suggesting an association of glutathione with the degree of suicide risk

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Science 334 , 14201424 (2011)