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Depositions of extracellular amyloid plaques and intracellular neurofibrillary tangles in the hippocampus and cortex are striking features of Alzheimers disease

Several of the chromophores and fluorophores (81, 82) responsible for lens colouration have been isolated and identified, including advanced glycation end products (8386), and tryptophan oxidation products (8789)

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This substantial rise in NO levels under SMG conditions likely reflects aberrant activation of NOS (e.g., iNOS) and indicates heightened oxidative stress and inflammation