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PulizziNLyssenkoVJonssonAOsmondCLaaksoMKajantieEet al

doi: 10.2174/0929867311320100009 147 SzkudelskaKOkuliczMHertigISzkudelskiT

doi:10.2152/jmi.55.241

Moreover, substances such as statins, angiotensin-converting enzyme inhibitors, or AT1-receptor blockers, which possess indirect antioxidant properties mediated by the stimulation of NO production and by the simultaneous inhibition of superoxide production, have been shown to improve vascular function in pre-clinical and clinical studies and to reduce the incidence of cardiovascular events in patients with cardiovascular disease (Mnzel et al., 2010)

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At daily intakes of 100 mg or higher, cells appear to be saturated, and at intakes of at least 200 mg, plasma concentrations increase only marginally [2,10,22,31,37]