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In the AIM-HIGH trial of patients with stable cardiovascular disease, the incidence of hyperglycemia (6.4% vs

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their reduction can lead to poor heart function and aging (148, 149)

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PLoS One 7(2):e32146 Licht T et al (2003) Induction of pro-angiogenic signaling by a synthetic peptide derived from the second intracellular loop of S1P3 (EDG3)