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Xun W, Shi L, Zhou H, et al

doi: 10.1016/j.molimm.2016.01.008 54 SonDOLiuWLiXPrudhommeGJWangQ

NAD + is an essential coenzyme and electron acceptor in catabolic pathways of metabolism (Reference Ryu, Nandu and Kim14)

By elucidating the structural mechanisms underpinning hOGA regulation, we provide a platform for the dissection of the role of the pHAT domain in mechanisms of modulating O-GlcNAc homoeostasis in such disease contexts and beyond