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Supplementary Figs

In a network meta-analysis of randomized controlled trials (RCTs), all SGLT2 inhibitors (SGLT2is) used as monotherapy were found to be significantly more effective than placebo in reducing HbA1c levels from baseline (mean differences ranged from 0.59 to 1.23%), increasing the proportion of patients achieving target HbA1c levels (odds ratios ranged from 2.18 to 3.45), and reducing mean body weight (mean differences ranged from 1.63 to 3.00 kg) (64) (Grade A)

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These modifications include: Eating a healthy and balanced diet