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Disturbances of mitochondrial biology, primarily mitochondrial bioenergetics, have a long history as a correlate of, and contributing factor to, the pathobiology of autism (48, 49)

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Published January 20, 2025.

If satisfactory clinical response has not been achieved, plasma levels should be measured to determine whether or not they are in the usually accepted therapeutic range (50-100 mcg/mL)

Addington J, Freimer M

The advantage of sEVs is that they are acellular and can be used off the shelf, can be designed to contain desired molecules, and the regulatory burden, involved in studying and manufacturing, is much less