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Fab fragments were obtained by proteolytic cleavage of IgG with papain (Worthington) and purified by Superdex200 10/60 (GE Healthcare)

Multifocal PVCs have different morphology as they originate from different foci in the ventricles

10.1021/jacs.0c05765

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2,1921 A level of less than 150 pg per mL (111 pmol per L) is diagnostic for deficiency

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