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Rheumatology 56 , 865868 (2017)

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Lactic acidosis Rising creatinine may occur

Genistein suppresses TNF--induced NF-B activation as well as nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor (IB) kinase and IB phosphorylation resulting in an inhibition of inflammation in the tumor microenvironment [154]

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Most recently, the ClearPoint system is being used with MRI-compatible materials for stereotactic localization with intraoperative imaging so that injection into the targeted structures can be visualized directly if the therapy is labeled with contrast agent